File talk:Signal transduction v1.png: Difference between revisions
Content deleted Content added
Possibe errors in MAPK section of image |
m ←Blanked the page |
||
| Line 1: | Line 1: | ||
At least one section of this diagram seems to be badly flawed: the canonical Raf pathway involves phosphorylation and activation of an MEKK kinase (aka STE11 or MAP3K), which in turns activates a MEK kinase (aka MKK, or STE7), which then in turn activates a MAPK, such as ERK, JNK or p38. So, the MEK just downstream of Raf should probably be a MEKK, and different classes of MKK should be upstream from the ERK and JNK MAPKs, with the MAPK entry redundant, and the MEK and MKK entries also mutually redundant. |
|||
It's quite possible that any of the reactions shown do exist somewhere in biology, but not be part of the canonical pathway. |
|||
